From: "Saved by Windows Internet Explorer 8" Subject: Raising the bar for biomolecular modeling Date: Thu, 17 Jun 2010 13:19:56 -0600 MIME-Version: 1.0 Content-Type: multipart/related; type="text/html"; boundary="----=_NextPart_000_0019_01CB0E1F.C7B6EBA0" X-MimeOLE: Produced By Microsoft MimeOLE V6.1.7600.16543 This is a multi-part message in MIME format. ------=_NextPart_000_0019_01CB0E1F.C7B6EBA0 Content-Type: text/html; charset="utf-8" Content-Transfer-Encoding: quoted-printable Content-Location: http://www.eurekalert.org/pub_releases/2010-06/uoc-rtb061110.php =EF=BB=BF Raising the bar for biomolecular modeling 3D"[=20 Public release date: 14-Jun-2010
[ | E-mail | 3DShare=20=20 Share ]

Contact: Leanne Yohemas
leanne.yohemas@ucalgary.ca=
403-220-5144
University of = Calgary=20

Raising the bar for biomolecular modeling

University of Calgary scientists discover = 'breakwater' to=20 help control electron transfer

3D""=20
3D"" 3D"" 3D""=20 3D"" 3D""
3D"" 3D""=20
=20

= IMAGE: The paper published in PNAS explores the role = of water=20 molecules (red and white) in forming a bridge (yellow) between = proteins=20 (green and blue) and that certain protein residues = (beige)...

Click here for more information. =

3D""=20 3D""
3D"" 3D""=20 3D""
3D""=20

Researchers at the University of Calgary found that amino acid = residues form=20 a type of barrier to help in the process of electron transfer between=20 proteins.

"This raises the bar for biomolecular modeling," says Dennis Salahub, = U of C=20 co-author of a paper published today in the prestigious journal = Proceedings=20 of the National Academy of Sciences (PNAS). "At a fundamental level, = it is=20 by far the most detailed insight that has been obtained for the dynamic = role of=20 water in this kind of electron transfer, or for that matter any = biochemical=20 reaction."

Electron transfer between proteins is the cornerstone of biological = energy=20 transfer. Every life-form uses this process to convert food or sunlight = into=20 chemical energy.

The interdisciplinary team of researchers found that the electron = travels=20 over a bridge made of a water molecule, while residues on one of the = proteins=20 form a sort of 'molecular breakwater' to keep other water molecules away = while=20 the electron travels across the bridge.

"You don't want too many (water molecules around the bridge) because = it gets=20 too crowded and they're all bumping into each other and you can't get = one to fit=20 at just the right position and the right angle (for the bridge) for any = length=20 of time," says PhD student and co-author Nathan Babcock. "It's like = being on a=20 crowded subway where you can't get comfortable."

In artificial mutations with a faulty breakwater, the water bridge is = disrupted and the rate of electron transfer is markedly reduced, he = says.

Using the CHARMM molecular simulation computer program, the research = team=20 examined a 40 nanosecond period of electronic coupling of the proteins=20 methylamine dehydrogenase and amicyanin from the bacterium Paracoccus = denitrificans.

"This is fundamental research but you can imagine how studies like = this can=20 be applied to various genetically modified organisms, and if you can = gain=20 control over some, you can use it to either speed up or slow down a = particular=20 reaction," says Salahub.

He says the work was made possible with the collaboration of two of = the U of=20 C's interdisciplinary research institutes; the Institute for = Biocomplexity and=20 Informatics (IBI) and the Institute for Quantum Information Science = (IQIS).

Babcock, whose background is in quantum information theory, was = pleased to do=20 research at the union of these two disciplines.

"When you think of quantum mechanics, usually you're thinking solid = state=20 semi conductors, atoms trapped with lasers, etc. It's usually cold = laboratory=20 stuff, not warm globby biological stuff," says the PhD student. "I think = the=20 union of biology and quantum mechanics is very, very exciting."

###

"Surface residues dynamically organize water bridges to enhance = electron=20 transfer between proteins" was published on June 14 in the journal=20 Proceedings of the National Academy of Sciences (PNAS) by Nathan = Babcock=20 and Aurelien de la Lande, now at the CNRS in France, Jan Rezac, now at = the Czech=20 Academy of Science, Barry Sanders, iCORE Chair of Quantum Information = Science=20 <http://icore.ca/research_qu= antum.htm>=20 at U of C and Dennis Salahub, Director of the Institute for = Biocomplexity and=20 Informatics and Professor in the Department of Chemistry.


3D"[ [ | E-mail | 3DShare=20=20 Share ]

  ------=_NextPart_000_0019_01CB0E1F.C7B6EBA0 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.eurekalert.org/images/back2e.gif R0lGODlhjAAkANUAANMjJOiKi/G5ueqYmd5ZWT4+PuFpaWpqZdEYGfrk5ON2dvvs7NpJSlpaVf3z 8/bS0vjc3PXNze6pqs0ICcwAAOyhovPBwfT09NYxMsnKrf78/P74+M0FBtg+PsoAAM8REs4NDvfX 1++wsdc3OM4LDM8PELGxsdjY2OXl5X9/f9DQ0J+fkK6urs0HCLm5ucwDA97e3pWVlYqKinFxcenp 6V9gVfTHyHp6eEVFRc4MDUtLS09PT////wAAAAAAAAAAACH5BAAAAAAALAAAAACMACQAAAb/QMoE lCsaj0hOi5RsFnnQqHRKrVqv2Kx2uxUSnUgEAKEEI7notHrNnnrNSkYFsogEAC/4s83v+9VvYAAD G1MRGHlMiot7fioXf5GSUIFNHRBWAmMvHRgIIxMdZI0rKaYxNGk7j1WmrqYwk7JUlUgMCVgMBAAY BgC7BhObUSkxKioyB6qsVMcqOyzHkLPUPLVGl1m+EhgDBAoEBB0MTMQsUM9QLjKmLlHIxamrPDDR VfNQpajVktcvAJiiJPAWABcUBR4MCJBQIcAABXc+TCBmDJk7HixcqHAxj6PGjDxWwWgQwwq+GTI2 NkjFz48/CVI0eSFQiIcvAgIKLahjYFcL/2IHTAWdRk/FjHNHp6xCeaVjA4otXQ5BYiBmCQ8YEH14 AIVACQNcY5KbCCXFubIlOTZI0eAcvig7Gihr+ohFiih2o/apBTCKBSIBNEDAk9NBJwVh/fr6WfYs xhQ0Trq9CFcGSbqP8d7V26ZW4CiIYOIiZ4OeGLCGfJpDdyDajmmtecTYfCGWSGgmH0WOdSE2ZzaV RjiIgjCwOAgM+lZA8M2g3+RkebCN6ztF0BnVg7YNWRc3FXwc2Zb8DXxqkQoCPwgPgFXEh6o2OQVA LBAcGS0weEvJT3QNM/JrBCIccR6IkAAe47RggWnv/VKIQwooMAqAFEYSyGemYaABe4owcP/QG7gs AAA4uihR4Yl8vNEXFOwFptUQheHBBCE8SEBBL8IQgeKOgExFE2gThPDAFxT8yGGRUYwFylRQFODk k1CecGINUDqJQoVvwASFDaHUWAYCXA2mxIBemmdEkzqkqaaaUlZYZZoZYDnEijywp0CdiaAX3z8R JHkNFHEFKmgBbUqCwgmIFjrFCTisuQMOK7yT6JVpoHBdbCZcKsVMGvgJUwVC6OleHiL4ZeYRgD6q aqNWynIAlFaY0OiqaUYB5VxoMMqqCRjBGgWnUIhYQmkOzBGsVnpC0UEiSaT66AqHJtrpJDfMWoAV 1dJaK5pp3qAGCtbyKquamw6BYQgSJeb/5wsY4gmGszrwuuikRU1KrwmRomDCvtCWtSY69K6a7aNt Ovmot1BksK8JcQKMKCQrrAntuNtSAmN6W0mxgFcctCvmuyGpKu87UEYK5Q3ZFnDDqzhQyWqj3g6M Q69PQhuuxNzq4G0GjjYqZcnapknxtb9efGxCzwnR7p4gB/0kuGryarDOMvfsqAkyh0zu0FAfnPMN XfestdUi/1u0glIE8559HpRAo6mMNDu2tmFLrSbKZD8bsaoycy3bv1nzMPUNewvdgJo8B01r4hVb Y/SWEr3RwYL7yWgGvHSHK/jdVR+uKj1rHuA0wi7XKvOVg3uuQ6QDF8536GBbW27HU3Dz/8Evbwu0 rB6Yv0yo5tbiraq+a+Kb96rBDt6ryJsfvOYNmd7tKOjMhz07fBoLWZPGu/M+NrT2As/5v0MfLzA6 s+7Qmszept/5889T/yivujbuhYZcPLCkHmStOnLyzHPfwLxVPt/l7UquI1vzdlA137FPfjiQ15MQ ZrEZbUEEluMfvP4HQbsdbIDLI1i0ULCABnpNdIr7nPtWBT4Soo5vHeQWrhxHBDpVIQFq49+ZxnYd lBGueAsUns5COLOwmTBNYUth/RgIxJQNzVtLlJcLFSUgdQkkIqfyXgpxUDXXCRGK1kLUCoeXPtVt 0Yso1IEy0vhECIJtaLMzwogE8AAIRIRAAov5kg73cMbjfRFzqhPizNKorSi4jpDQSx8hjQhBocnu bE3YhD902Lvila5nQpwL49ZEqJRda5PxU8fUOOktlpFygcpIYgQfWcE9unIPPowlyg6QARQcrgAN OEEpULaCXR4gUqw5GQI1JR1ZrmxkljLmyoAZsSdthweXYmaV4BiFIAAAOw== ------=_NextPart_000_0019_01CB0E1F.C7B6EBA0 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.eurekalert.org/images/share_icon.gif R0lGODlhCwALAJECAP////5tTP///wAAACH5BAEAAAIALAAAAAALAAsAAAIRVI5oye0J3okOWPto lvwtJxQAOw== ------=_NextPart_000_0019_01CB0E1F.C7B6EBA0 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.eurekalert.org/images/clear.gif R0lGODlhAQABAID/AMDAwAAAACH5BAEAAAAALAAAAAABAAEAAAICRAEAOw== ------=_NextPart_000_0019_01CB0E1F.C7B6EBA0 Content-Type: image/jpeg Content-Transfer-Encoding: base64 Content-Location: http://www.eurekalert.org/images/corner_tl.jpg /9j/4AAQSkZJRgABAgAAZABkAAD/7AARRHVja3kAAQAEAAAAPAAA/+4ADkFkb2JlAGTAAAAAAf/b AIQABgQEBAUEBgUFBgkGBQYJCwgGBggLDAoKCwoKDBAMDAwMDAwQDA4PEA8ODBMTFBQTExwbGxsc Hx8fHx8fHx8fHwEHBwcNDA0YEBAYGhURFRofHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8f Hx8fHx8fHx8fHx8fHx8fHx8f/8AAEQgABAAEAwERAAIRAQMRAf/EAE8AAQAAAAAAAAAAAAAAAAAA AAgBAQAAAAAAAAAAAAAAAAAAAAAQAAEFAAAAAAAAAAAAAAAAABEAQYETIxEBAAAAAAAAAAAAAAAA AAAAAP/aAAwDAQACEQMRAD8AT297kwEH/9k= ------=_NextPart_000_0019_01CB0E1F.C7B6EBA0 Content-Type: image/jpeg Content-Transfer-Encoding: base64 Content-Location: http://www.eurekalert.org/images/corner_tr.jpg /9j/4AAQSkZJRgABAgAAZABkAAD/7AARRHVja3kAAQAEAAAAPAAA/+4ADkFkb2JlAGTAAAAAAf/b AIQABgQEBAUEBgUFBgkGBQYJCwgGBggLDAoKCwoKDBAMDAwMDAwQDA4PEA8ODBMTFBQTExwbGxsc Hx8fHx8fHx8fHwEHBwcNDA0YEBAYGhURFRofHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8f Hx8fHx8fHx8fHx8fHx8fHx8f/8AAEQgABAAEAwERAAIRAQMRAf/EAE8AAQAAAAAAAAAAAAAAAAAA AAgBAQAAAAAAAAAAAAAAAAAAAAAQAAEFAAAAAAAAAAAAAAAAABEAQYETIxEBAAAAAAAAAAAAAAAA AAAAAP/aAAwDAQACEQMRAD8AT29DgyEH/9k= ------=_NextPart_000_0019_01CB0E1F.C7B6EBA0 Content-Type: image/jpeg Content-Transfer-Encoding: base64 Content-Location: http://www.eurekalert.org/multimedia/pub/rel/23109_rel.jpg /9j/4AAQSkZJRgABAQAAAQABAAD//gA7Q1JFQVRPUjogZ2QtanBlZyB2MS4wICh1c2luZyBJSkcg SlBFRyB2NjIpLCBxdWFsaXR5ID0gNzUK/9sAQwAIBgYHBgUIBwcHCQkICgwUDQwLCwwZEhMPFB0a Hx4dGhwcICQuJyAiLCMcHCg3KSwwMTQ0NB8nOT04MjwuMzQy/9sAQwEJCQkMCwwYDQ0YMiEcITIy MjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIyMjIy/8AAEQgA1QDI AwEiAAIRAQMRAf/EAB8AAAEFAQEBAQEBAAAAAAAAAAABAgMEBQYHCAkKC//EALUQAAIBAwMCBAMF BQQEAAABfQECAwAEEQUSITFBBhNRYQcicRQygZGhCCNCscEVUtHwJDNicoIJChYXGBkaJSYnKCkq NDU2Nzg5OkNERUZHSElKU1RVVldYWVpjZGVmZ2hpanN0dXZ3eHl6g4SFhoeIiYqSk5SVlpeYmZqi o6Slpqeoqaqys7S1tre4ubrCw8TFxsfIycrS09TV1tfY2drh4uPk5ebn6Onq8fLz9PX29/j5+v/E AB8BAAMBAQEBAQEBAQEAAAAAAAABAgMEBQYHCAkKC//EALURAAIBAgQEAwQHBQQEAAECdwABAgMR BAUhMQYSQVEHYXETIjKBCBRCkaGxwQkjM1LwFWJy0QoWJDThJfEXGBkaJicoKSo1Njc4OTpDREVG R0hJSlNUVVZXWFlaY2RlZmdoaWpzdHV2d3h5eoKDhIWGh4iJipKTlJWWl5iZmqKjpKWmp6ipqrKz tLW2t7i5usLDxMXGx8jJytLT1NXW19jZ2uLj5OXm5+jp6vLz9PX29/j5+v/aAAwDAQACEQMRAD8A 84ooorcQUVLbQG4l2bgqgFnc9FA6mpzfiE7bOFI0H8ToHZvck9PpSb6IxnValyQV39yXqU6K0Y7u 0uz5d/CsZPS4gXBX6qOGH61WvLN7OQAukkbcpKhyrj2/wpKXRihXvLkmuV/n6P8Ap+RHBEZ5hEGR SQWJc4AA6k1o6TYwTajHuubeWNcsygnJwCehAz0qPQ0R9SZJFDI0Eqtn02k/zAqLTJxbXZmbosUn 6qR/WplfVHNipVZKrCDtaP53/wAie41y6VnitruT7Oi7YzIoLqvA64z1rUsPEGmRaOtlc6arOn8R AZXPcnuDWBBexw3mntLZ28yWxOUZP9bk5O8jqOgx7VJqqhdTnKxRxI7eYiR/dCtyMe2DU8ibsKrl +Bmo0kmpb3Wm3XT119SGeaGZQY7cQsXZmAOeM/KB7Y/UmoaKkgt5rmURQQySyEEhY1LHA68CtUrI 7qdNU48qLOq6a2k3v2Z7iCc7FcPA25SCM9fWoLW8uLGYTW0rRv3x0I9CO4rQ0OGW2uftF1p0V9be WyrHct5ajPfIOTioE0qYsChjmCkblRucfjUKataRnicRhE3BzTXW9vue5pCytlMGqyq1uuPNe1jU ljg8Ef3VPv0rEnmnvNRaaKLdJcSHcoPABPf2Fa+ow3s/iiX7I0ivMR5ci9NhHH4YpmowraWyLFGs Fw6v5sakk7cgBufu5GTt7VF/xPGp1eVR5nzSmlb+6nrZ9dO/W3QgOqGyXyNLxEo4e4A/eSn1yfuj 2FVIA97fxLNIzmRwGZjk4z61KNNZbeOW4uIbcSjMayE7mHrgA4H1pYtPvY9Qt4Y4S0srDyirDa/u G6Yq/dSfc9KCotShSac3fXq36/1Y7DxRb32qRW1rYwb4l+dwGAx2Xgn61xuoafe2cpN1bSRLnClh xjtzUur3T3N1HcZKnylTg4wV4Iq5FcRaZd38V5LdtugUwRxuCgcgH5g2cjnpWcE4pWPPyzD1cPCE IuLVm7Wad7q+t3r02I7DQRcaVLql5dC2tI+jBN7N24H14rNt47O4RnW+WNQxAEsTBj74AOPzrpba 5S58NzwsixRR7ZNgOQATnisCaCK2tBLMpe5m+ZIFbbsX1Y4PXsKcZybYYbF16tWpzyaV7JJL/L73 exZgN5aKZreRLmFfvNE2So9wef0rQtDpesWklhMxtvMOVZfuhj149D6Vz1rdSWtxHdW7FHU5Gf1B qxq8CW2rTpCNi5DIB2BAOP1ocLvQqpguepaErSaumtNrbr5/nofT3g+3+yeENJt94fyrZE3AEZwP eiovA7tJ4H0VnYsxtEyT34ooPappqCUtz5Zoq1p+m3mq3i2lhbtPcMCQi4yQBk9arMpU4YYPoa2u r2NFFtNpaIuwLt0a7lH3nkji/Dlj/IVUlikgkMc0bxyDqrqQR+Bq9ZTRjS7qNnQSrJHNGrNtDYyD z+IpLpb3U/N1CW8F9IOZW3lnUe+ecD26VCl7zTOOE4QcnOSTcv0jb7+nncz6Z5r+Z5WTsxux71fl 014tJt9QNxbss0jIIlfMi47lewqvA8ccwaWPehGGA4OPaqZtVXu3SvYmsp/sy3Mo+8YjGv8AwLj+ WaozSmKP2YhT7DNa0el/arlksZxcw7d2FwsufTYxH5g9qJrSwt5Whu01CBx1DxL/ACzUcydziWJp SnNK7bt0d7Lut+5HbeHdUu5BdpA6WkQxNLINqKD33etaV9d2iTWdnapDJcmJY1uZ+hAzjj7qn/eP pVB72G0sms7Se8ntpWBmhkbykIHsCSf0ot47HS1FzqgdifmWDrnPQsT/ACqJXvd7GWI5JQ9pU5uZ bJKyffS/N23srE7aVfXE7QXsbRSbd0Uu0bM+hI4wen1xUdpqEegTiaCeU6gN0bKm5TDxjB7kn8vr Umo6817FttZGEbgZ+XHH0qu0v2yw8y6JaSMiPz9vzYxwGPcdvWj3muyIwlbEQcataNoXXuq//D28 k/zaJb/TtVGtrp97KpuZCvypIGUbgCOR7Us2ojT3a10siNEO1pyMvIfXn7o9hS6FbvFqsF5IVW2i Jd5SwxjBqtFYxtbfa7ufyIXYiMBNzyEdcD0Hqaq0b+RUo4V1OVpOEUtFrdtvtu0lt53NPTtTN5E9 rOkgk2ERTh2CoxPAbB6FsdehrH0SVbjUZLa4SSOXa8U6uPutg9+/OKt2EFnLepHHc3rBgcxLGq+Z gZwTu9s1TnuUn1ea+2+UZ5MkA8c8CptZvlMVRUZ1VRVk1fqrel++r7aepLq8/wBo1W4cfdD7EHoq 8D+VaOg3OrWdndXlrA81hb4WcggeUX+UEZ6E5x6etZgUXX2hSFMkeXR1GNyg8g/hzmi21O5hDJL5 VxEUKLFLGNqgj0HXHUZrS142R6lCFKdNUpx0jbTZ+qf6jN1rC4mjnE9sWDNE4KOOe3auhjk8M3d5 JqF7dzu8jbzA0ZUD2461zMk00775pDI2AASAMAdAAAABUdL2b7mFXL/aO6qSXpZOz+XlurG/e6vb 3d7cPZQMsMqBVRhjcVOOB26ViF1k81hGykN1J7fT60iSMgYAKf7pOcofUVq6dNoZiY6nHdLJ1IiO Vf8AqKlRcHc5I4d4J80YtpWWmrt/w34mets8ttG0KlyCVYKMkHtV/ULa6vmju0gcuY1WWNRlkYDH I9CADmrd/q0SQf8AErNpa2IIBQNmSTP94YzVCYaXDKREWWRxufySzR59icEfqKOZ6NCjiKzlGajt e3V2e6dtum1z6V8ERtF4I0aNxtdbVAR6cUUngfZ/whGjeXnZ9lTGevSig9uLbimz5etp3trhJk+8 pzjJGfbionw0zyBdu452gnCj0Ge1FFbWV7lqTSaT3Cpba6lsrhbiFsOufoR3B9iKioptXM5RU4uM tmX9O1K306/lmFpBc5RkSCdNyjcOuPYd6oVpaTd3Wn3UWoac4W8t8/wg/KRjOO/vWfJI0sryOcu7 FicY5NRC/VhCpGcUkrOKs/Xv8yaeykttPt9RR4maZmRVjf8AeRlSPvDsDz+VWo9UkmQQ3ZEq9t/P /wCqs3HNW/s/2ezW4mUFpwRCh7joWP8ASplBb9TnxsKdWEU1aS2a3v8A19yLULWtmHu0hMsi4ESO coh/vH19hWZNI9zM007GSRjlmbnJotpDaoETlQMANzTetVGL+0RhqEoScqur6Py/T9S5NqcMukW2 n/Z7dJoZWYyquJHBGcE9wK1pLKWPwxZW8UbPNeTeZtHX2/QZrno42llVI1LOx2gAcmvQ9V1K30my VEALxoEGOvTGBWc24tLfU487xbhOhTowu73t3a6/e/wODvre20y9itnBuJ2I8wR/KE9896z7nXYp l3LC0pXCoEJ+VR2q5PM9zO80h+Zzk4pkkawyNEGU4A+70wRmrUJPVs7KNCpzRlVleSV/89PuNDS5 rayu3uppl8yJSY4MHeWI4z6AZzmqAj3RPKcYQjr6k8U1o1jlVXZFmKDIJ5OOlPmkUhYY+Y0JOf7z dM/hXa8L7LmlPZbX/D7up6zwPsqlStVd09Fey72Vlba7bJLN/Kulbtgg/Qg1XBq7fw6dbW9u9nqB mkkg3TLJHs8t+4H97iqWPauOLTk7HJ7GUZe1a0ei+V7/AJi1ci02VoBcTPHbQN915Tjd9B1P5VYT TJtNtbXVL6FGtZlLwL5gPmEHGCAcjn17VA08l673d1smfeqndLtIBzjA9OAOOmaJS7HNWq1LtQ2W 7/Rf5v7mU38lXKrKz+4jbBqb7Dd+X5gtZ9nXd5ZxVr+2J4gYbMLabeJPLj2tn03Hmo4ru9ixJPqN 1Gx5wJGZvyz/ADqI1G9SJ1K9KbhK333f/kqt91yjznBpa2X1C1vlWK7kklZjt86SIK6e+4Hkexok 8PmOZYWvYt5BzhSQP6n8qr2i66ErMacdK3uv0evpp+h9GeBP+RE0T/r0T+VFSeDYfs/g3SId27Zb INwBGePQ80VB6EZKSTXU+VqKKK3AKKKKAFSR4nWRGKupyGB5FbEfiBnj8u7tLeYd3CAMai8PwXcu rJLZSWyT2ymdTcuFU7ecc8E+1ULu7F/ez3QKnzZC52jAyeeOlZy5W7MyrYGniI881t1vZ/5mzpNy LPX4LzTpordVy29xuKYByACOprK1C9k1C9kuZTy3AHoOwrYn0SC28KW+qiUpeZzjs4J4H4DnNc5P qERIMkDhz1Kd6zg7Nvc87C4t1Z63lGF4J27PW/e+mo6prW1nvZxDbRPLIeyioYbm3I3fZriU+jMI x+fJ/Sup0XWNRv3GlaTBp9hIVLZaTGQAT95u/FaSnZaHZVniZK2Gp8z7t2S8+/4Fi1hsfCKCa9In 1OQfLEnPlD6/1rB1S9Go5lhBKRtiQ46E9M+nQ4rPlkklmeSV2eRj8zMckn61d0OaOHWLfz5hFbSO EnYruBQ9cjvS5GnzdTihl06c/rMnz1evRei7eX3sz8E8AZJpksDwMssL7JSDvUjOfT6Vsx6KL/Vb q2sbyAW8e945538sMoyRjPc4q94G0dZNQudWZlMNghleF13bztOOT06VpLG08NQnWe9tPXovVvQ+ kwy5G4yTUn36bM52e2lMxVkYyMdy71xn3prOqu6rHHJh8H97ggfTFbGpXep67rSXV1N5QnRhCqgF QAMgKf6+9Yu5YoXH2fzGONu0fMOe3rx2rb26nSvUXvN3aT2+fXzM8TXozpvlvK7b3tb/AD8/8y5p V7Hp+ovdz2FvdqY2jWGfJVdwxn61Uq7JpklsqteSJb7hkI3Lkf7o5H44pGsQ1q9xazrOkePMG0qy Z6Eg9vcVzpx6HmxxNHRKWnfW337fiU5JZ0REBUxueA3ODnrRjjFXYtNnvLZpUX5YBz7nrj8qpYpU 7XbRVDEusnBu/K39z1N2G1k8QIjQOsN6uI5W6eYo/iXtuwMH86g1rR5NPuZyoPkxsilmPVmXPHrV FLqSCGNYnKkNvODjnt/KtzUdXimsNNkvzORM7tHJE210K4BJ7MO3PpWbvGV1seNN18LiI1KesHdW 9NfyTt2X3HN8dK11RdUsd8K7NVixtk6mRB1AHTOMfUADtV2DWbEMAdbvlXvm2jP61oy6UmrRxy2W tNJJF8yiWIAjPY4wR27UpzTM8Zj1LllONrdfea9H7q39T3PwTI0vgnRpG+81qhP5UVJ4PEo8IaUJ 12yi2XePQ45oqj6Kk04Ra2sfKlaGlmwimmbVLaaWHyWKKj7DuPCnOORUGp3Nnc6jK2n2ElpbFvkR 5d+0Y9etGoX91qhtjeTNL9miEMXbCDoOOtaNya0OhRhFrnd010/r7yrnA5q8umM2kS6j9ptgscip 5Jk/eNkZyB3FLpWqT6RdNcW8cLu0bR4mjDgA98HvWesapnaMZ603e+mxC5OV336DqlgtprmRY4Y2 YswUYHGT0qL8cVtWviS502AW1mkaxqc7scsfU0SbWyOPFVK0I/uIc0vWyLviy4it47XSIH3eQAZS D/FjAH865qNGlkSNcbmIUZOBz71de9tLmUtc2QjLHLSW7kH64PB/SodQsmsLtoGcOMBlccblIyDU w0XKc+XQWHpxw8k1LV69e70v1Y7U9NuNJ1CWyudhliIyY3DKcjPBHXrUt1eT61LYWwtrdJIUEEQi QIWyepPqfWopLa2GlRXK6kz3TSkNZmP7i44bd/StK8sdLtNFs5ILgy6mQJWCOCjqT90DHysvv1oc 7JuR7MaSqTjCm97X02b9L6f1YjFs1l9u0G7s401Jpo/3zMD5KruLcjPGCCcdhUkkH2Tw0xspTdmS YC6AtvlgZWIjIkPZuabp9lpvmaZeapqcYE9wTd26KWeJBzkkcHPTHvVayvra2h1SCS2nnjuoykCL OYxGckrnHBHPeokpTVlsylONFt7Sj9zd93s0T21hp+sa5JBE32IM+0yhMxNgdcZ+UEg8V0I1rw54 Ys7zTdPmN5PNGyzyNJtydpA28Y4z0qjrGmR2XgrTbtYjBc3TKLpQMbmUHGR7HNcg8kUZXzGCBv4s d68+MFi1zyk+SLa5e7T3ffXb7yKcaiUaaacnbX1/BaHSXscKwWFnbTB7yFBBbSFth7MNykZU8YH1 rGttbuYFuZTAi3ErBjcLCRLGehQDAA9c07T4Zr2Sb/SHe5ADwK/JbHVc/TkVb85Z7maO+KKl2Nyy qmNjjoTjrzwfrXq05uClHueXCnGV6U976ro767P+tzIDSPlpGJJPVjk/jU9sLhpQtqXMrnywsf3i T2x70t1ai18v/SIJt67v3L7tvPQ8darp+7mWZflkQ5VxwQaTTtZHbThSUXCaurHW+Ey9hrdxo+oR tCZgVZJRgrIBkZ+tZOr6DqENzcrZWxlAOY9pHftU8FxI2l3N5cyNDPLIcXjP+8m4xsGe2cEkemKz IZ7aa2jguRsK52XSjJGezjuPfqPes7++7HkSo1YV5Yih8D916X1SvfS22m19yaHRbmIA3xW1iH35 JSM/gvU0zUrxLuWNIVKWsCeXErdcdyfcnmrOqac6W8F0sQB2BJdh3DI6MCOoYfrmsjBHWrhrqb4S 1dKtKSdtElsuj6vXz7bbiFEIwVXH0q9bR6dHpkhjN3Hq5mXyHjfEYTocj1qnmlq3FPc77KzXc+rf CcF3a+FNLgv2LXaW6LKSQctjnkcflRVfwKSfAuilmLH7ImSTkniisRpJKy2PltVLnAxnr1q1qWm3 ekXz2V7GI50AJUMGGCMjkcUaZc2lnfCe806K/iCMvkykgZIxnj0qqSzsSSSepJOa1u03fY0tGSSg nfr/AMASikJAGT0rVm0qIaLFfW1y08qnF3D5eBBk/J82fmz+lNySdiVCTjzW0Mutewe0vYbOxuYY tPRZSX1QwvJngna2Dj0GKyUG5wvU4JA9ccmun8VX88aQ6YJZIeFlu7MW4hjjlwMFQP8AZIrOdpvk Oijz0V7bTy9e6815mbfnw+mkxyWr3a3sTKkiMu9J+eXH90dOKnupiRcalqOkK0GpRH+z5PPIaPad u4qPTGMHrULXWh2Wt2jW0Fxe2SqnnJcpjLH73KkcDPH0qnrEdouo3MNhcvPZhiIZSpU7T7HpUxXN K+qsTVhCNpK0m1v1V7XVumqWu/nZixaXeTaXcalHFm0t3VJH3AYLdOOpqvaSpbXAkmhW6iGR5MhI Az3BGCDn3qvbpJBB5JneRM5AY9KkrXl5l7yM1NwbVNuwmBztUKvYDtS1raFDbGeS5vYPNt4l5U9M +pqhHay3c8otIHkAy2FGcLUqau12E4tpPudnHqkPiDwReW99NDHd28gaME/e79Pf5q5LVb+K91GS Wys7a0tWUKYUTOcD7wJ5UnrXT/DSNW126ZgCVt+Mj/aFcdN808hAxlzx+NedgkqeJrUY7XUvnLf8 jWcYqhTsttPkti9Z3Ucl3BGJoLZyPKaV0GYx13DHfHfrUmpvai8iVbnzvIYxGaKP5JVB4cZ5HB5+ lZGAG3YGfWpTOzWyQYXYrFhxzk4/wr0uV9WYz5JNOKtZfj3LN/pV3p+pmwlj3THaU28hwwypHqCC KnkSy0p/LZFvbteGyf3SH0/2j+lO0WeSXW7UyyO5RSse45xhTgCo9eudVurqE6pC1vOkCLGGiCHZ /CffPrSbd+U5ZQdaq4SlaKte27vf52Vuncu3Fxqf/CNST3SWc1pqEgjUuFMkew5wq9UFYH0o3yPj zH3EfkPYVd0m0tbvUY4rzUBYQ4Ymcx7wCAcDHuaauo3S1OuFOlCSpxdoJ9F072G2ep3NmFRJXMQO THuwMdwPSuiTxHFJbBbmwivI143lAXA/2h/WsktfajpVpaGC3S2s92LkoI92TzubvVRbWRJN1teQ PIP+eUuD+GcZqJRi/U8XG4TB1p3ulJfL72tn/WpNq2rWLR+VY6PCJZDgOQwVPc809P7JdFVo3DAY LJLjJ+hBqGW4uLhHhvFJkQbkZ1AYeo9xVDHFNRfRlUcI3DljOUWv7zd/nofVPgsRr4L0cRZ8sWqb dxycYopngQf8UJon/Xon8qKk9SKaikz5aoXAlRzkhTyoOAw9D7UUVs0mrMuMpQfNF2Zb1S8i1G/k uIbGCzjcACCDOwYGOM+vWrPh6XVbG4mk0aCWRlhYzLGu792Rhic9OO9ZdSwXVxalzBNJF5ilH2MR uU9j7UNXQKVi54f1X+ydZt72KaaONCVZ4gA5QjBxkelTXEUOqzarerqAVISrxC9fM04PG0YGMjis qON5XCRozueiqMk1b0qxF7eqJflto/nnc9FUdfz6UlScrLqKrio0uepZJWem9k+1/wAOpTwcZwce uOKtWNi155jtIsNvEAZZn6LnoMdyfSjUdRnvbhmVituD8luDhFXsMevvWxpcWjXGlTx313dW8UbG XCopZ3C8Dr068+9bWgm23ojjlUruKio2lLtrb/g/h6ma0ejD5Vub3P8AfMK4/LOa2NDj01fOgiW3 vrh+Ns6FGTv0+lctK88ssgs1WNjny4V5bAGcluvT0xVuwKJPJBNIUuJjhJ2PIkHQE+h6flUNKsnC K1+Y2quFlGpOTtZOz5Xo/RfqaGsXzfPbLpos8gfKucEevvn1qeWBtF8P2lxHLJFe3JY7VfHyepH5 1EfEOpSFLVo0abcE5HJPQA0+7n8Q2utkNDNFqFghLCNd5jBHJOMjGD1rjjTlpFqy66npupHWSd30 NTwFayWlxca7cSeTY28bKzMP9YT2H0rn/s9vqd3d3a3Edpb+czssgJZELcEADnr0rqdBv5fFGjan pmqTFmx5qXDcBW68446iuY0+O1OmzRs8j3FzGdkQUpgqT0Y8HnBwPSufC3eJrzn8SsvluvW+t+wT tyQS2/q5Dc22nzpeXGk3E8ttaSJE/wBoQKxLDqMdsjpWditTR4QLa905R+8ubcSAY5Lr8/54zWZX rSjZJ/1c82hVc5zT6PT0aVvxuPgmkt545ojiSNgyn3Famoi51t/t0MslztUK0Jbc8IHYDuvpiqll d2kNpfQz2Uc8s0Y8mV3KmEg8kY68etO0kWAuZHvru5tgsTNFJbrlt/YH2rFtN6bo1q4ep7taGj28 n5f1sVvskxt/NGxQX2HLjcpxnJXqB71oNdrp9qIRp8RuWbf9pljPAxjCg8Y+veotY1G31G6BtJrq SAIuRcSBzuxzyAKdPqL6jBawX+oSPHaIY4VEe4IvoDxUK0mpMKzqQi6GIVtdUru/zXT8O9yjcXdx dtuuJnkI6bjwPoO1bWh2uoJp1zcWs2nGO7JtDDcANJ0JyoPT0zWVbpp7xAz3FxHIeyxBgP1rb0bQ 7O8mSS31hBKpBVTHtYEHPQmnNxSOOvjaeEoy5E46W+F2/IybGVnzBO+YMbctyYyeMg/0psGk39zP JFDbO5jYqxAwAfr0rduLC0XVbsraNNdhmbyml/cwg/xPjv6Dk1U1TxJHBb/Z7XT1vbsnBluGJii+ i5wTUKevuo8+jjak6j+rQ+K2+y89H/l5H0X4MgktvBmkQSgCRLVFbByM49aKi8BtI/gPRGlKGQ2i Fii7RnHYdqKZ78L8q5tz5booq9o1kNQ1i2tWHyu/zf7o5P6CuiMXJpImrUjShKpLZK/3C22ltcaP d6h9oiQW7KohbO+TJx8vGOKbHpGpSruSwuCvr5ZrrvFcljZaWliLqS3iM3m/Z4WUKCRjcQRxVWXX 7XW3s9PvZJtKtUjcz3C5Z5Tj5BtPQe9aShGnUcKj+44aeLq4rCwxOFho20+bTa21nr17LTcydL05 7a5S8uLpLYQsGwCC30PYfiapX2r/AGqa4tbaFbe0VwwRCf3me7E8nvgdqXUdPu7JbN7hJDb3S+Zb 4wxZM4yACadrH9l/al/sy3uLdSi+ak7ZZWA6dPrx70vaq3JDYpYObqRr12nLZLa1tdVv6X2exDpu mXer3q2djF5s7KWC7gvAGTyasapqFxrNsJ798yx7YIigCfKByDjr2qhbxXM1wqWuN5BySSABjkkj pitHUbu91+73xweaLeELi3g2gIvBYhf5mskr35lod05WcVTnaW7te6Xr5/5kN7rF1qEtrJcFM20Q hj8tAvyjscdarajGj3koxlGbcv48irEx04aNbCOKYagZGMrlwUKdgBjg1LDf2n9nx2q6Zbve8j7V czPtA7AKMD86qErr3SK1N06inNWstfR2a/rzJYJH07VbG9+yx37GJZWiliLIxII5HfpTRc6tbahO IopbGa83K26TYSp/hG45x1HPpTLe41K71ORpporCawhRLQQtsEjDr3xkgk56dqlnuLbVLu/v9f8A tpvniHlOsYw0o45J6jjtSqxV09fut/maYapBQkoOL02um7eX9bEx1i00/wAM/wBl2rk31zl5yBwF zjr+GKL1GVNPFz5iW8Me4gDlR2/M1J4T0KK3v4LuaKGT7XDJLDvHyrsbHI+o/Wqt/f8A9srdPLew pLbuS6OW3StnAAGMcDP51x0o0/bScNrtvW+u1vlt8jfETfs/dW+not3/AF3JbnXB9nsZdPDQXihv tYEa4Yg/KwbryOo9vesq8MU8zXMChEc5aMf8s27j6elP0y8j0/UY7uS0hu0RWUwTjKNkY5/nQ93D LqHntaRwQuFWSGHO3oASM+/NdkL3cXsclaMUlUhfmV7ruvII9Rli0e50wRQNDcOruzRguCpyMN1F LqdtY2sqCx1AXcZiVnYpsKseq4749ajv7M2V00O4On3o5B0dT0Ip3nWB0drd7ANfecHW7LnKpj7u 3pSnFrRbmtGpTklJ6xaKLA7dqjaCeSKmt0hM8SzuyQFgHZBkqvcgVOwi/smMj/XGdgfptGKqUkY0 nzc0vO33Fm/jtItQnSwmkmtFbEUki7WYepFdB4ZtIIbC61e5Tb5KHyG35EhPHTHauct0jMgMzARj r71rTa5CbZrRbRZLcRlEBJUBuzYHp2FRO791HHjXKv8A7NTW+77Lt6sqvbXCJcXyyhlfDF0bOSe3 1FZ2BXouiaC974PjltzEZpFclCAQDk4yO/auMFre2BeW5tLS6BO3KodqNnkYB4/GphPVo5MDjVzz ptap2Wyulp/mfSfgT/kRNE/69E/lRUngti/gvR2MYiJtUJQLjbx0xRQe4ndXPlc8HB4NW9Mvm03U oLtRny25HqDwf0NTLrl4V2XHk3Sek8Qf9ev61aRZG0t9WTRbT7NHKImkLkgMenybv/rV1x5U01I4 6jqTg6dSndNW0a/WxV8QLJ/bl35pLb23AnupGR+hFSrNfeKNWtYbu9iEm1YEmnO1UUdASB+FZ1zc zXly887l5HPJqJSYpknR2SRCCrKcYI5FZ1W5NuJ04OCp0oQq9FbTvb8rly+sbnQpra5lldJg7x7O f3YU4yM9ic03U9QutU1Ca9vpfNuJSC74AzgYHT2FT63f3GpXaSXczzy+Uod3OSxPJ/nWUjFG8lj2 yhPcen4Vcktl0/pnPQcre0k783+en4FtblktDFCQEl++ynlsdvpS2d/d2Du1ncywPIpRjG2CVPaq UMYjaQqMBmJrTsr9ILO6s5La3YXJQG4ePdJAAc5T3qZtm2GjG15dXqzPCBWJycn1OcU6ptQSxh1d rSwu5rqBjmOaWPYW4ySR25zQ4WAZADv2zRCDcb7DxGKhCfLdt9O/kPg0ybUY1EFqZdhIJ2jA79Tw K07URaZbzWV/MlysnS3j+d0P++eB+ZqlpMV9qupRWMCtPcNkpEzBUYAEnkkAdK0LKytvEF7fHU7m 6klV4lgtDMN0mW2lAzdQMg8noKuNWK1jvtrscdfB1ZLlqbP3ko6ve9r9H8l6m7o81tHZ6SRBILuB ZVgiuGC5DMSSR3riJYJP+EjvreWS1i86ZWaRm+VcnBII9DnPFb2r2Vro3iBbSSF5p4tmxlcN5bdN vPB60/XLUaPd6hbWNrYPHE7Qzspy+48ZyewJ7VlSw6oNtLmer8tdfzdzRYx1FFt8kNF7y1b73v26 W3OfubcQTSLHKs8SsVWaPO1/cVDW3Dp+nJpr3F7DLFqaPkW6BRFMjEAFn/hx+talvfWel6LqYuY9 IjvnCC0jWESnr8x3ZODj1q7Whzz0NPb81f2FJqbezTsn+b/AxtMT7dazQXQ/0WCNpFn7wnsAe4J7 Vk9qs3WpXl6DHNcF40cgKo2oSO4GB/Kq2RkZIAJxk9KdSSS9BYOlNyb/AJnol/wbavrovzJo7uSK IQmOKWHcW2SL3xjII5FN+0YbKW0K/wC8S/8AOrk1tYXKadDpT3E95MNs6uAF8wngIfT61DDFbQXc sF+zqUV1ZYyCyuMgAj6isLx08zo+p3cnbbfW34XG3KTLbQzqVQT5ORGp+6cYGRx+FW4tQ0/yUSbS oi6jBkViN3uRmrGhWUmtJNpm6JVRGnSSSQL5ZA569QfSs/UtMuNJu/s1z5RfaHDRSB1YEZBDDg0K K2OGGGjJOnNNNPdNq6e2q+75F+TW4ooU+wxvbsnZWOCPSsmDUtUsdTNxbSRtbyfN8xxn6+9R06ND 5crF0Eca7ypOG687fX1xUumkZ/2dSprbmT3vqfVHg+5a78H6TcMMNJbIxGc9qKb4LmW48F6PMqoq vaoQE+6OO1FI9KMVCKjHZHzvqvh9YdRltrV0NzHgyWqyhzyM/u2HDcduorL1d7F74jSVuYLLC5ju GDNuHU+1VFdkcOjFWU5DA8g1paxidbO/2hXuoyZABgF1O0n8eDXTKKmr9jClUqYeooXupXSfXbbz 0vrv6mZRRV210ye70+8vY3gEVoFMivIFZtxwNo71J0EJje4UyopYqAHA5I9/pSQ6bd3/ABbwuSvP mYwqn1JPAqOOSSGQSROyOOjKcEVPc6je3iBLi6lkQdFZuPyq7xerOVwrRXJC1vO+ny6/ehLW1jnl kjkuoLd1Jx5hJUnJzhgCKjihMxUxkOjEgSLyvHXmq7zCJ40K8SHbu9DzitfT45UhMaDLTNuWPpkg df8APpVxipuxyzrTw9Ju97O2vz1/4co3lrbx3EEg3edEDt5457momJZix6mnSbzI3mZ355zTaiUr vTY68PQ5EpTd5dxVZlO5SQfUHFbOh2mlyQXV1qQuS8YAtxE21S3fceuMelZ+nafNqEjrGDtjXc7Y 6Cpr2QwW6WqcKOvvTjTTXNLYyxOKcZqhSfvv8E/1Kt5cm7u5Jum48Adh2qvJlgxJy3XOe9OxV19L kTSI9SM9vseUxiHf+9477fT3rNy1uzsjTSgopaLQosWYuCSUYD5SeCOv9a0vDmqx6DeT3Bs3mfy2 Nu642wSEY3MCMEf1qosEk7IkETOQmWCjOPf9KLmFIYoNlysjvlpVjOVX+6Ce56mqqQUnd7I5sLXd KChB2lLT5X1v9wW1q1ybpxIdyR+ZsxwcHk/kf0qFSokUugdAQSp6MPSprRbsSvJZ9UjYy9MeXjDd frUAFD2RrTbVSSv2+X9b/MuaneQXmqS3VnZx2MTsCkEJO2Pjt/OqZJLsx5djksepPvR34o71NjYP mAO1yrdmHUVeW/tjpENrcW1w94JnczJIPKKnGFKnkd+R39ao96DUuCbv1Kcm6bpt6PX59ybNptJ3 XCn08sN+oP8ASoo1+0SKkH74k4AQZJP0oqXTbmTTNQkuYj8sqBZE7nHQg0ndK61OSp7WlByh7z7P /gI+oPAsRh8DaLEV2lLVAV9OKKk8GSifwbpEozh7ZDz9KKzN6bbim9z5etII5nZ55DHbxjMjAZP0 A9TV7Xo76Ce2jurEWsDwh7ZS+SIj06dzyT9aplcaWrf3piD+A/8Ar1XeR5CC7s+BgbjnA9K6JLRL 5kUZXnKb13S8u7Xn59vmNGMjIyM81c1W5tJb2Q6TaSW1nIqgxyy7yCOp/OqdFRKKludFOo4O6/q5 c0u6srS5eS/s0u4vKYCJpCmGPAOR6GqdIUDsMqGI6cZqSSCaKYwyROkoOCjKQwP0NNJ3YScOVWVn 1Eht47m5RJtwiGGcr1ADZ4961dUkhh1E32lNcyWKOvkyyxY5PYkcZ4P4VQnK26/ZlYGQjMhH8qZH qt4lnJpAnkW0dhMYg3ysRx09q0ndaRdmedh3GcnUqRUo6pfO+pu6pLperxwy2+Y75x+8Re3bkd/a sGS1njuzatE/nhtuzack/Sn2V29hepdwqhlQEKXXIGe9ddb69a6okJvVjtLp90a3KAblGOcE9Oo/ Wt0oV9W7S/M4Zyr5auWEeen011X6tEMktv4a0I2Suj385DThTnHoPoK5p7eaaze/ZlKCURnnnJGf yq1rGh3elP5j/vrdj8s69D9fQ1HYzodNv7SQ8yKskf8AvKf8CaU23LkkrJdC8NGMKX1mnLncmrvy bSdl0sZzLuUjJGe4rUg0wiG3n1GQrG4JGwZeQZzn0UfWsvr0rRtvsp0TUIprq6jupAq20UePLfn5 934elc8eSL5po9Sv9YnTVKhK13t39PP5FIai03mW1s0gQ8yRqTg+gPrxj86tR6PeNEsrolvCeQ87 iMEe2eT+FQzeHprHRre+mU+TfSMVYyZY7eMHnI49fWoCScAknAwMnOBVuSestTmpU5xi407Kz1ur v9DTe4trDTZ7S2mE89xgSyqCFVQc7VzycnrUGnHSx9o/tRbo/uj5At2A+ftuyOlU8citK+3azdzT 6VohhiihDSR2xLLGBgFznoKzqT8jswuHUW1zavVt+nl6WRTZLcadFJ9od71nIeMR4RUA4Oc8knNQ AUlL2pRioqyNalSVSTnN3bLVtp17ew3EtrayzR26hpWjUkID3NQlFESOJY2LdUU8r6E/X+laGpXU tuIbaLTp9ML26iVcuBcD++2fU54rJVY0OBsTOTzxmo5+uyRsqX2ErydrWZdg1NrKxu7QqpiugoZt mSpU5GD+Yp16NMFrZ/YWujcbD9q84ALuzxsx2x60ajDYwSRJY3M058secZItm2TuF9R71S61SWt7 mLknFRtquvc+pvAn/IiaJ/16J/KijwJ/yImif9eifyorN7knzXCon8P3Cj79vMsh/wB1htP6gfnW dU1rcG2lJ6o6lHX1U1E4CuVByAeDXTLVJnNTThUlF9dV+v46/MfDBNcyiK3hkmkPRI1LMfwFR1Ys tQu9LulvLGZ4rhAdrIcHnqK2LBfDx0i7/tZb2LUS3mW7Kc7h/dZe2euetZ31sdLsoc1/l1foc79q WzkSdgxCHd8vYjp+ta/iW+vob6zj1G0nTWrjMktxO3LIVG3AyRwAQDTob+11PTE0swQ2bROZIp3j ALMequ/XHp2qhBpp1LxHbC61JEc5ieWV96RKB1JBP5Ukn/E6Cqzi39VaTku3W/n1S/DUxbJ5ptRu ZX/1f3Uz7GtWBljnV3GV5DfQ9ao21rHZzSxRXcd0qsw8yM5U89varXXrVptO5ioxqU3HpqjWttIh fWI7O9vktIHUsLgqWHTI49+lZTvucR5yEGP1NbFkbTUoXjv1v2eCFmiezTcysOhb0X1NZNqoSVR5 Rn3YUoc5b6Ec5py+NpbE0+Z0IuavOLd9rNbXXma+k67qECmxSFb6OQbVt5AWz7U6KGxsonF3NGNS kRk8qIl4YSfVvXH1qC5vprAS2dvZHT3+7Luz5x9iTggewArKUqp3t91eTWyqWstzhlg+bmqJezT3 S3fruvu1ffoOZSjFCOQcGq/+vmaTcyqnyJtOPqakmdxbtIf9YxwPqaREEcaoOgFYNK1u56NOUnUU usfzLcp/dW0RYDPAyf0qOeCa2maG4hkhlX7ySIVYfUGriXMlhcwXEQjZ0XAEiBhyMdDVe8vbnULp 7m8nknnfG6SRsk4GBTqJqflYjBzjKje2rbdyvzUsNzcWokEE8kQlXY+xiNy+h9qiNWdOsn1LUYbN JYYXlbaJJ32ov1PapOgq9Ku6VbWd1frDf3hs7dlYmUR78HHAx7mrFzJYGCz0vZaQXcU7rNeJIX8w ZGCcHGB2xVPU7WG11Ce3tL5bmKNh5dzECobvkA1HPzJ8ps6ThKPtNE7P5Be313fziW8uJJ3VQitI ckKOgqpLDHOmyVFdfQitDU5tPmliOnWstvGIlEiySbyz92HoD6VTqltqZStfTYKKKDTEfUvgX/kR NE/69E/lRSeBP+RE0T/r0T+VFYvcZ8t0kYC3AMgZoiPmCnDD6Z4rqv8AhXHi/wD6Adx/30v+NH/C uPF//QDuP++l/wAa2UkiJRUlqY32jToIy1tb3Dz9muGXavuAOp+tUGZnYsxLMeST3rqP+FceL/8A oB3H/fS/40f8K48X/wDQDuP++l/xpudyKdGMHfVvuzmIYJbiVYoIpJZW+7HGpZm78AdatJc6aNJa 1FnuuTMGa6Vyp2d0A6c+tdDB8P8AxrazpPb6PdRSocq6OoKn2OaY3w68Yu5d9FuWZjksXUkn86zk lJ6vQ6oVORe6ve79v+HOTvn0WLXpINCinhtHXcEuCC4OB3HvmnVvH4X+LI74XZ0G6fjG1GTIzxnr Vs/DfxeCR/Yk5x3DL/jVXRzwVvdMuVpNJ1bytE1U3EUqKrOiGPfuGDGeeRS6jaJpN3LFPHcWWo25 DGJSHXPBG1gcj9a37HwD4it47lbzwtdXDyR7YXWZV8lv73B5+lUz8O/GMh3volyWPUs6k/zqYuMb xXU1qxlU5akpfDpv0XRrt5/iZ81ncavYXuvXGoRNJuDCKVmMsozjPQ4x7npVC3s7OeG4W+vvshWE yxr5ZcykHheOmfWumtPAXjSzlM0OkXUbBTwrr83t1/nUf/Cs/FUcUDjSbqSRh+93upbcPx6HtWkY pR0epzVasnValH3d9L+bt/TOd+26ZJpLWi2RkvUlDrebyABzldvQ/WqoGTgd66SL4b+MSGd9CuAz sSfmT/Gpv+FceL44mlGiTs4OFQMuSfXr0qY9mzScrRcoxtfW3r0OYmlMsxA+6gxUeeK6eP4a+MET B0S4LHkncvJ/Onf8K38X/wDQDuP++k/xqpTTdyaFL2VNQOWwTzjgUV1lv8PfGlpeRXMOj3KvGwcK WQqSOmQTU1/4F8a6nfz3tzokpmmbc5XYoz9AahN9TomoWXL8/U5kXsC6Q9l/Z9sZmlEguyv71RjG 0H0qmDXbaf8ADDxBOLn7dp13blIi0OxUfzH7Kfm4HvVP/hXHi/8A6Adx/wB9L/jTuiTlaWup/wCF ceL/APoB3H/fS/40f8K48X/9AO4/76X/ABouhHLVdtbK3uNNvJ3vUiuIdpitypJmBPOD2xW3/wAK 48X/APQDuP8AvpP8au6d4L8aaYLnyvDvmGeIxEzKj7Ae65PB96TemhUbXXNse4eBf+RE0T/r0T+V FS+DrK403wfpNldxtHcQ2yJIjHJBA5zRWQO19DcxRiiigQYoxRRQAYoxRRQAYoxRRQAYoxRRQAYo xRRQAYoxRRQAYoxRRQAYoxRRQAYoxRRQAYoxRRQAYoxRRQAYooooA//Z ------=_NextPart_000_0019_01CB0E1F.C7B6EBA0 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.eurekalert.org/images/eutube/icon_image_tiny.gif R0lGODlhEAAMAOZFAA0NDSwsLPj4+AYGBqqqqmtra2pqamVlZd7e3hcXF4qKil1dXWdnZ7e3twIC AoSEhAsLC52dnfX19QQEBFJSUrm5ucnJydzc3BQUFPr6+ktLS/b29t3d3dnZ2QMDAxUVFQoKCsfH xzk5OTs7O7Ozs9vb225ubtTU1GRkZAgICMbGxikpKaSkpMPDw+Hh4fT09FZWVouLi2lpaeDg4HR0 dBAQEERERHBwcFlZWQkJCR4eHs/Pz8zMzIWFhW1tbREREbS0tNDQ0AEBAQ8PDwAAAP///wAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACH5 BAEAAEUALAAAAAAQAAwAAAeCgEWCgz1DQwWCCCohF4OCHABERBAIGSMmNzZFApwSDJKSMCUULxsG OAGpK6CgAAM1Px8DrEQHBAQotABDoB4RQQYFFiwToIagPh0YkkMnNMa8REIkC6waDQ7M0Q4NIqwJ LSDakkJAn6AyFULjkgsuOpIJMwfGOawPOwoKPDHrkimBAAA7 ------=_NextPart_000_0019_01CB0E1F.C7B6EBA0 Content-Type: image/jpeg Content-Transfer-Encoding: base64 Content-Location: http://www.eurekalert.org/images/corner_bl.jpg /9j/4AAQSkZJRgABAgAAZABkAAD/7AARRHVja3kAAQAEAAAAPAAA/+4ADkFkb2JlAGTAAAAAAf/b AIQABgQEBAUEBgUFBgkGBQYJCwgGBggLDAoKCwoKDBAMDAwMDAwQDA4PEA8ODBMTFBQTExwbGxsc Hx8fHx8fHx8fHwEHBwcNDA0YEBAYGhURFRofHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8f Hx8fHx8fHx8fHx8fHx8fHx8f/8AAEQgABAAEAwERAAIRAQMRAf/EAE8AAQAAAAAAAAAAAAAAAAAA AAgBAQAAAAAAAAAAAAAAAAAAAAAQAAEFAAAAAAAAAAAAAAAAABEAQYETIxEBAAAAAAAAAAAAAAAA AAAAAP/aAAwDAQACEQMRAD8AT2F7gwUH/9k= ------=_NextPart_000_0019_01CB0E1F.C7B6EBA0 Content-Type: image/jpeg Content-Transfer-Encoding: base64 Content-Location: http://www.eurekalert.org/images/corner_br.jpg /9j/4AAQSkZJRgABAgAAZABkAAD/7AARRHVja3kAAQAEAAAAPAAA/+4ADkFkb2JlAGTAAAAAAf/b AIQABgQEBAUEBgUFBgkGBQYJCwgGBggLDAoKCwoKDBAMDAwMDAwQDA4PEA8ODBMTFBQTExwbGxsc Hx8fHx8fHx8fHwEHBwcNDA0YEBAYGhURFRofHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8f Hx8fHx8fHx8fHx8fHx8fHx8f/8AAEQgABAAEAwERAAIRAQMRAf/EAE8AAQAAAAAAAAAAAAAAAAAA AAgBAQAAAAAAAAAAAAAAAAAAAAAQAAEFAAAAAAAAAAAAAAAAABEAQYETIxEBAAAAAAAAAAAAAAAA AAAAAP/aAAwDAQACEQMRAD8AT2FDkyUH/9k= ------=_NextPart_000_0019_01CB0E1F.C7B6EBA0 Content-Type: text/css; charset="iso-8859-1" Content-Transfer-Encoding: quoted-printable Content-Location: http://www.eurekalert.org/eurekalert.css BODY { FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; FONT-SIZE: 12px } P { FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; FONT-SIZE: 12px } TD { FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; FONT-SIZE: 12px } CENTER { FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; FONT-SIZE: 12px } UL { FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; FONT-SIZE: 12px } DL { FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; FONT-SIZE: 12px } DT { FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; FONT-SIZE: 12px } DD { FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; FONT-SIZE: 12px } BODY.eurekalert { BACKGROUND-COLOR: #ffffff; MARGIN: 0px } A { COLOR: #2c56ac; TEXT-DECORATION: none } A:active { COLOR: #2c56ac; TEXT-DECORATION: none } A:visited { COLOR: #666666; TEXT-DECORATION: none } A.small { FONT-SIZE: 10px } A.blacklink { COLOR: black; TEXT-DECORATION: none } A.blacklink:visited { COLOR: black; TEXT-DECORATION: none } A.redlink { COLOR: #cc0001; TEXT-DECORATION: none } A.redlink:visited { COLOR: #cc0001; TEXT-DECORATION: none } .redhead { COLOR: #cc0001 } BODY.release { FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; BACKGROUND: = #ffffff; COLOR: #000000; MARGIN-LEFT: 50px; FONT-SIZE: 12px; = MARGIN-RIGHT: 50px } BODY.release A { TEXT-DECORATION: none } BODY.release A:link { BACKGROUND: none transparent scroll repeat 0% 0%; COLOR: #2c56ac } BODY.release A:active { BACKGROUND: none transparent scroll repeat 0% 0%; COLOR: #2c56ac } BODY.release A:visited { BACKGROUND: none transparent scroll repeat 0% 0%; COLOR: #666666 } BODY.release A:hover { TEXT-DECORATION: none } H1.title { FONT-SIZE: 18px } H2.title { FONT-SIZE: 14px } H2.subtitle { FONT-STYLE: italic; FONT-SIZE: 12px } SPAN.unpaid { COLOR: #ff0000 } FORM { MARGIN: 0px } INPUT { FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; FONT-SIZE: 12px } SELECT { FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; FONT-SIZE: 12px } TEXTAREA { FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; FONT-SIZE: 12px } .required { COLOR: #cc0001 } .imagecaption { FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; FONT-SIZE: 10px } .AA_Headline { MARGIN: 9px 0px; FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; = FONT-SIZE: 18px; FONT-WEIGHT: bold } .BA_Subhead { MARGIN: 0px 0px 9px; FONT-FAMILY: Verdana, Arial, Helvetica, = sans-serif; FONT-SIZE: 14px; FONT-WEIGHT: bold } .BB_SubheadNoSpace { MARGIN: 0px; FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; = FONT-SIZE: 14px; FONT-WEIGHT: bold } .CA_Body { MARGIN: 0px 0px 9px; FONT-FAMILY: Verdana, Arial, Helvetica, = sans-serif; FONT-SIZE: 12px } .CB_BodyIndent { MARGIN: 0px 0px 9px 12px; FONT-FAMILY: Verdana, Arial, Helvetica, = sans-serif; FONT-SIZE: 12px } .CC_BodyHanging { TEXT-INDENT: -12px; MARGIN: 0px 0px 9px 12px; FONT-FAMILY: Verdana, = Arial, Helvetica, sans-serif; FONT-SIZE: 12px } .DM_DisplayMoreRed { MARGIN: 0px 0px 9px; FONT-FAMILY: Verdana, Arial, Helvetica, = sans-serif; COLOR: #cc0001; FONT-SIZE: 10px } .FA_Footer { MARGIN: 0px 0px 9px; FONT-FAMILY: Verdana, Arial, Helvetica, = sans-serif; FONT-SIZE: 10px } .FB_FooterReverseSmall { MARGIN: 0px 0px 9px; FONT-FAMILY: Verdana, Arial, Helvetica, = sans-serif; COLOR: #ffffff; FONT-SIZE: 10px } .HA_HeaderHeadline { FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; FONT-SIZE: 18px; = FONT-WEIGHT: bold } .HB_HeaderBody { FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; FONT-SIZE: 12px } .HC1_HeaderSmall { LINE-HEIGHT: 10px; FONT-FAMILY: Monaco, Verdana, Arial, Helvetica, = sans-serif; FONT-SIZE: 10px } .HC2_HeaderSmallReverse { PADDING-BOTTOM: 0px; LINE-HEIGHT: 10px; MARGIN: 0px; PADDING-LEFT: 0px; = PADDING-RIGHT: 0px; FONT-FAMILY: Monaco, Verdana, Arial, Helvetica, = sans-serif; COLOR: #ffffff; FONT-SIZE: 10px; PADDING-TOP: 0px } .IA_InputNormal { FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; FONT-SIZE: 12px } .IB_InputMedium { FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; FONT-SIZE: 11px } .IC_InputSmall { FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; FONT-SIZE: 10px } .NA_NavigationHeadline { MARGIN: 0px 8px 0px 16px; FONT-FAMILY: Verdana, Arial, Helvetica, = sans-serif; FONT-SIZE: 11px; FONT-WEIGHT: bold } .NB_NavigationText { MARGIN: 0px 8px 0px 16px; FONT-FAMILY: Verdana, Arial, Helvetica, = sans-serif; FONT-SIZE: 12px } .NC_NavigationTextSpace { LINE-HEIGHT: 16px; MARGIN: 0px 8px 0px 16px; FONT-FAMILY: Verdana, = Arial, Helvetica, sans-serif; FONT-SIZE: 11px } .ND_NavigationTextHanging { TEXT-INDENT: -12px; MARGIN: 0px 8px 0px 28px; FONT-FAMILY: Verdana, = Arial, Helvetica, sans-serif; FONT-SIZE: 12px } .ND_NavigationTextHangingNS { MARGIN: 0px 8px 0px 16px; FONT-FAMILY: Verdana, Arial, Helvetica, = sans-serif; FONT-SIZE: 12px } .NE_NavigationTextHangingSpace { LINE-HEIGHT: 16px; TEXT-INDENT: -12px; MARGIN: 0px 8px 0px 28px; = FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; FONT-SIZE: 12px } .NE_NavigationTextHangingSpaceNS { LINE-HEIGHT: 16px; MARGIN: 0px 8px 0px 16px; FONT-FAMILY: Verdana, = Arial, Helvetica, sans-serif; FONT-SIZE: 12px } .NR_NavigationRule { MARGIN: 0px } .NX_NavigationTextReverse { MARGIN: 0px 8px 0px 16px; FONT-FAMILY: Verdana, Arial, Helvetica, = sans-serif; COLOR: #ffffff; FONT-SIZE: 11px } .OA_CalloutHeadline { MARGIN: 0px; FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; = FONT-SIZE: 14px; FONT-WEIGHT: bold } .OB_CalloutText { MARGIN: 3px 8px 3px 16px; FONT-FAMILY: Verdana, Arial, Helvetica, = sans-serif; FONT-SIZE: 12px } .OD_CalloutTextBold { MARGIN: 3px 8px 3px 16px; FONT-FAMILY: Verdana, Arial, Helvetica, = sans-serif; FONT-SIZE: 12px; FONT-WEIGHT: bold } .OC_CalloutTextHanging { TEXT-INDENT: -12px; MARGIN: 3px 8px 3px 28px; FONT-FAMILY: Verdana, = Arial, Helvetica, sans-serif; FONT-SIZE: 12px } .OE_CalloutTextHangingBold { TEXT-INDENT: -12px; MARGIN: 3px 8px 3px 28px; FONT-FAMILY: Verdana, = Arial, Helvetica, sans-serif; FONT-SIZE: 12px; FONT-WEIGHT: bold } .OR_CalloutRule { MARGIN: 0px } .OS1_CalloutSpecial { MARGIN: 3px 8px 3px 16px; FONT-FAMILY: Verdana, Arial, Helvetica, = sans-serif; FONT-SIZE: 10px } .OS2_CalloutSpecialRed { MARGIN: 3px 8px 3px 16px; FONT-FAMILY: Verdana, Arial, Helvetica, = sans-serif; COLOR: #cc0001; FONT-SIZE: 10px } .SR_SpecialRed { MARGIN: 0px; FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; COLOR: = #cc0001; FONT-SIZE: 10px } .SS_SpecialSmall { MARGIN: 0px; FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; = FONT-SIZE: 10px } .XX_Smallest { FONT-SIZE: 10px } .XX_Small { FONT-SIZE: 11px } .XX_Medium { FONT-SIZE: 12px } .XX_Large { FONT-SIZE: 14px } .XX_Largest { FONT-SIZE: 18px } SPAN.headingtext { COLOR: #575858; FONT-WEIGHT: bold } SPAN.navlinkessay { COLOR: #000000; FONT-SIZE: 12px } SPAN.navlinkessaysel { COLOR: #000000; FONT-SIZE: 12px; FONT-WEIGHT: bold } SPAN.biglinkessay { COLOR: #000000; FONT-WEIGHT: bold } SPAN.navlinka_Essays { COLOR: #cccccc; FONT-SIZE: 11px } SPAN.navlinka_Essay_TITLE { COLOR: #ffffff; FONT-SIZE: 11px } UL.expertmedia { LIST-STYLE-TYPE: none; MARGIN-TOP: 0em; MARGIN-BOTTOM: 0em } LI.expertmedia { PADDING-BOTTOM: 3px; PADDING-LEFT: 3px; PADDING-RIGHT: 3px; = PADDING-TOP: 3px } A.emerging_sidebar:link { COLOR: #cccccc } A.emerging_sidebar:visited { COLOR: #cccccc } A.emerging_sidebar:active { COLOR: #cccccc } A.emerging_sidebar_a:link { COLOR: #cccccc; FONT-WEIGHT: bold } A.emerging_sidebar_a:visited { COLOR: #cccccc; FONT-WEIGHT: bold } A.emerging_sidebar_a:active { COLOR: #cccccc; FONT-WEIGHT: bold } A.emerging_body:link { COLOR: #575858 } A.emerging_body:visited { COLOR: #575858 } A.emerging_body:active { COLOR: #575858 } UL.emerging_resources { LIST-STYLE-TYPE: square; MARGIN-TOP: 0em; MARGIN-BOTTOM: 0em } LI.emerging_resources { PADDING-BOTTOM: 1px; LIST-STYLE-TYPE: square; PADDING-LEFT: 1px; = PADDING-RIGHT: 1px; PADDING-TOP: 1px } A.nih_sidebar:link { COLOR: #cccccc } A.nih_sidebar:visited { COLOR: #cccccc } A.nih_sidebar:active { COLOR: #cccccc } A.nih_sidebar_a:link { COLOR: #cccccc; FONT-WEIGHT: bold } A.nih_sidebar_a:visited { COLOR: #cccccc; FONT-WEIGHT: bold } A.nih_sidebar_a:active { COLOR: #cccccc; FONT-WEIGHT: bold } A.nsf_sidebar:link { COLOR: #3c75cf } A.nsf_sidebar:visited { COLOR: #3c75cf } A.nsf_sidebar:active { COLOR: #3c75cf } A.nsf_sidebar_a:link { COLOR: #3c75cf; FONT-WEIGHT: bold } A.nsf_sidebar_a:visited { COLOR: #3c75cf; FONT-WEIGHT: bold } A.nsf_sidebar_a:active { COLOR: #3c75cf; FONT-WEIGHT: bold } A.nsf_sidebar:hover { COLOR: #3c75cf; FONT-WEIGHT: bold } A.highlightbkgrd:hover { =09 } A.nsfkeywordSrch:link { COLOR: #000000; FONT-WEIGHT: bold } A.nsfkeywordSrch:hover { BACKGROUND-COLOR: #ffffff; COLOR: #3c75cf; FONT-WEIGHT: bold } A.nsfkeywordSrch:active { BACKGROUND-COLOR: #ffffff; COLOR: #000000; FONT-WEIGHT: bold } A.nsfkeywordSrchA:link { BACKGROUND-COLOR: #ffffff; COLOR: #000000; FONT-WEIGHT: bold } A.nsfkeywordSrch:visited { COLOR: #000000 } TD.marine_sidebar { COLOR: #333333; FONT-SIZE: 11px } A.marine_topmenu:link { FONT-FAMILY: Helvetica, Verdana, Arial, sans-serif; COLOR: #336666; = FONT-SIZE: 11px; FONT-WEIGHT: bold } A.marine_topmenu:visited { FONT-FAMILY: Helvetica, Verdana, Arial, sans-serif; COLOR: #336666; = FONT-SIZE: 11px; FONT-WEIGHT: bold } A.marine_topmenu:active { FONT-FAMILY: Helvetica, Verdana, Arial, sans-serif; COLOR: #336666; = FONT-SIZE: 11px; FONT-WEIGHT: bold } A.marine_sidemenu:link { COLOR: #666666; FONT-SIZE: 11px } A.marine_sidemenu:visited { COLOR: #666666; FONT-SIZE: 11px } A.marine_sidemenu:active { COLOR: #666666; FONT-SIZE: 11px } A.marine_sidemenu_hl:link { COLOR: #666666; FONT-SIZE: 11px; FONT-WEIGHT: bold } A.marine_sidemenu_hl:visited { COLOR: #666666; FONT-SIZE: 11px; FONT-WEIGHT: bold } A.marine_sidemenu_hl:active { COLOR: #666666; FONT-SIZE: 11px; FONT-WEIGHT: bold } A.marine_blacklink:link { COLOR: #333333; FONT-SIZE: 11px; FONT-WEIGHT: bold } A.marine_blacklink:visited { COLOR: #333333; FONT-SIZE: 11px; FONT-WEIGHT: bold } A.marine_blacklink:active { COLOR: #333333; FONT-SIZE: 11px; FONT-WEIGHT: bold } A.marine_blacklink_small:link { COLOR: #333333; FONT-SIZE: 10px; FONT-WEIGHT: bold } A.marine_blacklink_small:visited { COLOR: #333333; FONT-SIZE: 10px; FONT-WEIGHT: bold } A.marine_blacklink_small:active { COLOR: #333333; FONT-SIZE: 10px; FONT-WEIGHT: bold } A.marine_bluelink:link { COLOR: #003c67; FONT-SIZE: 11px; FONT-WEIGHT: bold } A.marine_bluelink:visited { COLOR: #003c67; FONT-SIZE: 11px; FONT-WEIGHT: bold } A.marine_bluelink:active { COLOR: #003c67; FONT-SIZE: 11px; FONT-WEIGHT: bold } .marine_browntext { COLOR: #d2d1bf; FONT-SIZE: 11px } A.blacklink125 { COLOR: black; FONT-SIZE: 14px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.blacklink125:visited { COLOR: black; FONT-SIZE: 14px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.redlink125 { COLOR: #cc0001; FONT-WEIGHT: bold; TEXT-DECORATION: underline } A.redlink125:visited { COLOR: #cc0001; FONT-WEIGHT: bold; TEXT-DECORATION: underline } A.bluelink_submit { COLOR: #2c56ac; FONT-SIZE: 16px; FONT-WEIGHT: bold; TEXT-DECORATION: = none } A.bluelink_submit:visited { COLOR: #2c56ac; FONT-SIZE: 16px; FONT-WEIGHT: bold; TEXT-DECORATION: = none } A.redlink_submit { COLOR: #cc0000; FONT-SIZE: 14px; FONT-WEIGHT: bold; TEXT-DECORATION: = none } A.redlink_submit:visited { COLOR: #cc0000; FONT-SIZE: 14px; FONT-WEIGHT: bold; TEXT-DECORATION: = none } .redlink_inactive { COLOR: black; FONT-SIZE: 14px; FONT-WEIGHT: bold } A.dissertations_features { FONT-STYLE: italic; COLOR: black; TEXT-DECORATION: none } .clearfix { DISPLAY: inline-block } .clearfix:after { DISPLAY: block; HEIGHT: 0px; VISIBILITY: hidden; CLEAR: both; CONTENT: = "." } * HTML .clearfix { HEIGHT: 1% } .clearfix { DISPLAY: block } .clearfix { HEIGHT: 1% } .clearfix { DISPLAY: block } ------=_NextPart_000_0019_01CB0E1F.C7B6EBA0 Content-Type: application/octet-stream Content-Transfer-Encoding: quoted-printable Content-Location: http://www.eurekalert.org/eurekalert.js function visit(newURL) {=0A= if (newURL !=3D "") {=0A= location=3DnewURL=0A= }=0A= }=0A= =0A= =0A= var SciBubble, HHMINavPop;=0A= =0A= var currentNavURL;=0A= =0A= var win =3D null;=0A= =0A= =0A= // (C) 2000 www.CodeLifter.com=0A= // http://www.codelifter.com=0A= // Free for all users, but leave in this header=0A= function printWindow(){=0A= bV =3D parseInt(navigator.appVersion);=0A= if (bV >=3D 4) window.print();=0A= }=0A= =0A= /*=0A= Auto center window script- Eric King = (http://redrival.com/eak/index.shtml)=0A= */=0A= function NewPopupWindow(mypage,myname,w,h,scroll){=0A= LeftPosition =3D (screen.width) ? (screen.width-w)/2 : 0;=0A= TopPosition =3D (screen.height) ? (screen.height-h)/2 : 0;=0A= settings =3D=0A= = 'height=3D'+h+',width=3D'+w+',top=3D'+TopPosition+',left=3D'+LeftPosition= +',scrollbars=3D'+scroll+',resizable,menubar'=0A= win =3D window.open(mypage,myname,settings)=0A= if(win.window.focus){win.window.focus();}=0A= }=0A= =0A= /* Adding "back" and "forward" buttons to the feature popups */=0A= function NewFeaturePopupWindow(mypage,myname,w,h,scroll){=0A= LeftPosition =3D (screen.width) ? (screen.width-w)/2 : 0;=0A= TopPosition =3D (screen.height) ? (screen.height-h)/2 : 0;=0A= settings =3D=0A= = 'height=3D'+h+',width=3D'+w+',top=3D'+TopPosition+',left=3D'+LeftPosition= +',scrollbars=3D'+scroll+',resizable,menubar,toolbar'=0A= win =3D window.open(mypage,myname,settings)=0A= if(win.window.focus){win.window.focus();}=0A= }=0A= =0A= /* For the "Be on the cover of Science" game - position the window = higher */=0A= function NewBOTCOSPopupWindow(mypage,myname,w,h,scroll){=0A= LeftPosition =3D (screen.width) ? (screen.width-w)/2 : 0;=0A= TopPosition =3D 10;=0A= settings =3D=0A= = 'height=3D'+h+',width=3D'+w+',top=3D'+TopPosition+',left=3D'+LeftPosition= +',scrollbars=3D'+scroll+',resizable,menubar'=0A= win =3D window.open(mypage,myname,settings)=0A= if(win.window.focus){win.window.focus();}=0A= }=0A= =0A= =0A= self.onerror =3D function() {=0A= =0A= return true;=0A= =0A= }=0A= =0A= function di(id,name){=0A= =0A= if (document.images) {document.images[id].src=3Deval(name+".src"); }=0A= =0A= }=0A= =0A= =0A= =0A= // function that displays status bar message=0A= =0A= =0A= =0A= function dm(msgStr) {=0A= =0A= document.returnValue =3D false;=0A= =0A= if (document.images) { =0A= =0A= window.status =3D msgStr;=0A= =0A= document.returnValue =3D true;=0A= =0A= }=0A= =0A= }=0A= =0A= var showMsg =3D navigator.userAgent !=3D "Mozilla/4.0 (compatible; MSIE = 4.0; Mac_PowerPC)";=0A= =0A= function dmim(msgStr) {=0A= =0A= document.returnValue =3D false;=0A= =0A= if (showMsg) { =0A= =0A= window.status =3D msgStr;=0A= =0A= document.returnValue =3D true;=0A= =0A= }=0A= =0A= }=0A= =0A= =0A= =0A= =0A= // function that will load the bubble with URL, opening the bubble if = necessary (one bubble per page)=0A= =0A= function loadBubble(URL) {=0A= self.name =3D "scipix";=0A= SciBubble =3D window.open(URL, window.name+'bubble', = 'toolbar=3D0,location=3D0,directories=3D0,status=3D0,scrollbars=3Dyes,res= izable=3Dyes,width=3D430,height=3D350'); =0A= SciBubble.focus();=0A= =0A= =0A= }=0A= =0A= // function that will load full size popup with URL, opening the bubble = if necessary (one bubble per page)=0A= =0A= function loadRepak(URL) {=0A= self.name =3D "scipix";=0A= SciBubble =3D window.open(URL, window.name+'RePak', = 'toolbar=3D0,location=3D0,directories=3D0,status=3D0,scrollbars=3Dyes,res= izable=3Dyes,width=3D580,height=3D420'); =0A= SciBubble.focus();=0A= =0A= =0A= }=0A= =0A= =0A= =0A= // function that safely closes the bubble=0A= =0A= function closeBubble() {=0A= =0A= if ((SciBubble !=3D undefined) && (SciBubble.close !=3D undefined)) {=0A= =0A= SciBubble.close();=0A= =0A= }=0A= =0A= }=0A= =0A= =0A= =0A= =0A= // function that (re)opens a navpop with URL (one navpop per page)=0A= =0A= function loadNavPop(URL) {=0A= =0A= HHMINavPop =3D window.open(URL, window.name+'navpop', = 'toolbar=3D0,location=3D0,directories=3D0,status=3D0,scrollbars=3D1,resiz= able=3Dno,width=3D340,height=3D420'); =0A= =0A= HHMINavPop.focus();=0A= =0A= }=0A= =0A= =0A= =0A= // function that safely loads and focuses on the main window with URL=0A= =0A= function loadMain(URL) {=0A= =0A= if (window.opener) {=0A= =0A= window.opener.location =3D URL;=0A= =0A= window.opener.focus();=0A= =0A= }=0A= =0A= }=0A= =0A= =0A= ------=_NextPart_000_0019_01CB0E1F.C7B6EBA0 Content-Type: application/octet-stream Content-Transfer-Encoding: quoted-printable Content-Location: http://s7.addthis.com/js/200/addthis_widget.js /* (c) 2008, 2009, 2010 Add This, LLC */=0A= var addthis_conf=3D{ver:200};function = addthis_invoke(e,c,d,f){addthis_config.username=3Df||_ate.pub();addthis_s= hare.url=3D(c||b.addthis_url);addthis_share.title=3D(d||b.addthis_title);= var = b=3Dwindow,g=3Daddthis_share.url.toLowerCase(),a=3Daddthis_share.title.to= LowerCase();if(g=3D=3D=3D""||g=3D=3D=3D"[url]"){addthis_share.url=3Dlocat= ion.href}if(a=3D=3D=3D""||a=3D=3D=3D"[title]"){addthis_share.title=3Ddocu= ment.title}_ate.as(e);return false};if(!window._ate){var = _atd=3D"www.addthis.com/",_atr=3D"//s7.addthis.com/",_atn=3D"//l.addthisc= dn.com/",_euc=3DencodeURIComponent,_duc=3DdecodeURIComponent,_atc=3D{dr:0= ,ver:250,loc:0,enote:"",cwait:500,tamp:-1,xamp:0,camp:1,vamp:1,famp:0.02,= pamp:0.2,damp:1,abf:!!window.addthis_do_ab};(function(){try{var = F=3Dwindow.location;if(F.protocol.indexOf("file")=3D=3D=3D0){_atr=3D"http= :"+_atr}if(F.hostname.indexOf("localhost")!=3D-1){_atc.loc=3D1}}catch(L){= }var = J=3Dnavigator.userAgent.toLowerCase(),M=3Ddocument,t=3Dwindow,H=3DM.locat= ion,O=3D{win:/windows/.test(J),xp:/windows nt 5.1/.test(J)||/windows nt = 5.2/.test(J),osx:/os = x/.test(J),chr:/chrome/.test(J),iph:/iphone/.test(J),ipa:/ipad/.test(J),s= af:/safari/.test(J),web:/webkit/.test(J),opr:/opera/.test(J),msi:(/msie/.= test(J))&&!(/opera/.test(J)),ffx:/firefox/.test(J),ff2:/firefox\/2/.test(= J),ie6:/msie 6.0/.test(J),ie7:/msie = 7.0/.test(J),mod:-1},f=3D{vst:[],rev:"78223",bro:O,show:1,dl:H,upm:!!t.po= stMessage&&(""+t.postMessage).toLowerCase().indexOf("[native = code]")!=3D=3D-1,camp:_atc.camp-Math.random(),xamp:_atc.xamp-Math.random(= ),vamp:_atc.vamp-Math.random(),pamp:_atc.pamp-Math.random(),afamp:_atc.af= amp-Math.random(),ab:"-",seq:1,inst:1,wait:500,tmo:null,cvt:[],avt:null,s= ttm:new = Date().getTime(),max:4294967295,sid:0,sub:!!window.at_sub,dbm:0,uid:null,= spt:"static/r07/widget19.png",api:{},imgz:[],hash:window.location.hash};M= .ce=3DM.createElement;M.gn=3DM.getElementsByTagName;window._ate=3Df;var = u=3Dfunction(r,p,q,d){if(!r){return q}if(r instanceof = Array||(r.length&&(typeof r!=3D=3D"function"))){for(var = l=3D0,a=3Dr.length,b=3Dr[0];l-1){x.onReady();return}if= (O.msi&&window=3D=3Dtop){(function(){if(x.isReady){return}try{M.documentE= lement.doScroll("left")}catch(d){setTimeout(arguments.callee,0);return}x.= onReady()})()}if(O.opr){M.addEventListener("DOMContentLoaded",function(){= if(x.isReady){return}for(var = d=3D0;d";q=3Dp.getElementById("_atssh"+l)}b.opp(q.sty= le);q.frameborder=3Dq.style.border=3D0;q.style.top=3Dq.style.left=3D0;ret= urn q},off:function(){return Math.floor((new = Date().getTime()-f.sttm)/100).toString(16)},oms:function(d){var = b=3Df;if(d&&d.data&&d.data.service){if(!b.upm){if(b.dcp){return}b.dcp=3D1= }b.trk({gen:300,sh:d.data.service})}},omp:function(b,d,e){var = a=3D{};if(b){a.sh=3Db}if(d){a.cm=3Dd}if(e){a.cs=3De}f.img("sh","3",null,a= )},trk:function(e){var = d=3Df,i=3Dd.dr,b=3D(d.rev||"");if(!e){return}if(i){i=3Di.split("http://")= .pop()}e.xck=3D_atc.xck?1:0;e.xxl=3D1;e.sid=3Dd.ssid();e.pub=3Dd.pub();e.= ssl=3Dd.ssl||0;e.du=3Dd.tru(d.du||d.dl.href);if(d.dt){e.dt=3Dd.dt}if(d.cb= ){e.cb=3Dd.cb}e.lng=3Dd.lng();e.ver=3D_atc.ver;if(!d.upm&&d.uid){e.uid=3D= d.uid}e.pc=3Dwindow.addthis_product||"men-"+_atc.ver;if(i){e.dr=3Dd.tru(i= )}if(d.dh){e.dh=3Dd.dh}if(b){e.rev=3Db}if(d.xfr){if(d.upm){if(d.atf){d.at= f.contentWindow.postMessage(m(e),"*")}}else{var = l=3Dd.get_atssh();base=3D"static/r07/sh19.html"+(false?"?t=3D"+new = Date().getTime():"");if(d.atf){l.removeChild(l.firstChild)}d.atf=3Dd.ctf(= );d.atf.src=3D_atr+base+"#"+m(e);l.appendChild(d.atf)}}else{f.qtp.push(e)= }},img:function(l,r,b,p,q){if(!window.at_sub&&!_atc.xtr){var = d=3Df,e=3Dp||{};e.evt=3Dl;if(b){e.ext=3Db}d.avt=3De;if(q=3D=3D=3D1){d.xmi= (true)}else{d.sxm(true)}}},cuid:function(){return((f.sttm/1000)&f.max).to= String(16)+("00000000"+(Math.floor(Math.random()*(f.max+1))).toString(16)= ).slice(-8)},ssid:function(){if(f.sid=3D=3D=3D0){f.sid=3Df.cuid()}return = f.sid},sta:function(){var = b=3Df;return"AT-"+(b.pub()?b.pub():"unknown")+"/-/"+b.ab+"/"+b.ssid()+"/"= +(b.seq++)+(b.uid!=3D=3Dnull?"/"+b.uid:"")},cst:function(a){return"CXNID=3D= 2000001.521545608054043907"+(a||2)+"NXC"},fcv:function(b,a){return = _euc(b)+"=3D"+_euc(a)+";"+f.off()},cev:function(b,a){f.cvt.push(f.fcv(b,a= ));f.sxm(true)},sxm:function(a){if(f.tmo!=3D=3Dnull){clearTimeout(f.tmo)}= if(a){f.tmo=3Df.sto("_ate.xmi(false)",f.wait)}},xmi:function(r){var = b=3Df,p=3Db.dl?b.dl.hostname:"";if(b.cvt.length>0||b.avt){b.sxm(false);if= (_atc.xtr){return}var = l=3Db.avt||{};l.ce=3Db.cvt.join(",");b.cvt=3D[];b.avt=3Dnull;b.trk(l);if(= r){var = q=3Ddocument,e=3Dq.ce("iframe");e.id=3D"_atf";f.opp(e.style);q.body.appen= dChild(e);e=3Dq.getElementById("_atf")}}}});K(f,{_rec:[],rec:function(e){= if(!e){return}var = q=3Dj(e),b=3Df,d=3Db.atf,l=3Db._rec,w;if(q.ssh){b.ssh(q.ssh)}if(q.uid){b.= uid=3Dq.uid}if(q.dbm){b.dbm=3Dq.dbm}if(q.rdy){b.xfr=3D1;b.xtp();return}fo= r(var = R=3D0;R=3D(i=3Di.charCodeAt(0)+13)?i:i-26)= })}for(var p=3D0;p-1||i.indexOf(S.replace(/^ = /g,""))=3D=3D=3D0){T|=3Dr}}return T}function R(){var = V=3D(t.addthis_title||w.title),S=3Ds(V),U=3Dw.all?w.all.tags("META"):w.ge= tElementsByTagName?w.getElementsByTagName("META"):new = Array();if(U&&U.length){for(var T=3D0;T-1&&S.indexOf(_atd+"book")=3D=3D-1){va= r w=3D[];var = aa=3DS.substr(ad);aa=3Daa.split("&").shift().split("#").shift().split("=3D= ").pop();af.sr=3Daa;if(ae.vamp>=3D0&&!ae.sub&&aa.length){w.push(ae.fcv("p= lv",Math.round(1/_atc.vamp)));w.push(ae.fcv("rsc",aa));af.ce=3Dw.join(","= )}}if(ae.upm){af.xd=3D1;if(f.bro.ffx){af.xld=3D1}}if(p){if(ae.upm){if(q){= f.sto(function(){R();ae.atf=3Ds=3Dae.ctf(d+m(af))},f.wait);t.attachEvent(= "onmessage",ae.pmh)}else{s=3Dae.ctf();t.addEventListener("message",ae.pmh= ,false)}if(f.bro.ffx){s.src=3Dd;f.qtp.push(af)}else{if(!q){f.sto(function= (){R();s.src=3Dd+m(af)},f.wait)}}}else{s=3Dae.ctf();f.sto(function(){R();= s.src=3Dd+m(af)},f.wait)}if(s){ae.atf=3Ds=3Dae.get_atssh().appendChild(s)= }}if(t.addthis_language||N.ui_language){ae.alg()}if(ae.plo.length>0){ae.j= lo()}}catch(ac){}}f.ed.addEventListener("addthis.menu.share",f.oms);t._at= e=3DP;t._adr=3Dx;try{var = E=3DM.gn("script"),v=3DE[E.length-1],y=3Dv.src.indexOf("#")>-1?v.src.repl= ace(/^[^\#]+\#?/,""):v.src.replace(/^[^\?]+\??/,""),z=3Dj(y);if(z.pub||z.= username){t.addthis_pub=3D_duc(z.pub?z.pub:z.username)}if(t.addthis_pub&&= t.addthis_config){t.addthis_config.username=3Dt.addthis_pub}if(z.domready= ){_atc.dr=3D1}if(z.async){_atc.xol=3D1}if(_atc.ver=3D=3D=3D120){var = D=3D"atb"+f.cuid();M.write('');f.igv();f.lad(["span",D,addthis_share.url||"[url]"= ,addthis_share.title||"[title]"])}if(t.addthis_clickout){f.lad(["cout"])}= if(!_atc.xol&&!_atc.xcs&&N.ui_use_css!=3D=3Dfalse){n()}}catch(L){}o.bindR= eady();o.append(h)})();function addthis_open(){if(typeof = iconf=3D=3D"string"){iconf=3Dnull}return = _ate.ao.apply(_ate,arguments)}function = addthis_close(){_ate.ac()}function = addthis_sendto(){_ate.as.apply(_ate,arguments);return = false}if(_atc.dr){_adr.onReady()}}else{_ate.inst++}if(_atc.abf){addthis_o= pen(document.getElementById("ab"),"emailab",window.addthis_url||"[URL]",w= indow.addthis_title||"[TITLE]")}; ------=_NextPart_000_0019_01CB0E1F.C7B6EBA0--